INT250873

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Context Info
Confidence 0.55
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fgf8)
Anatomy Link Frequency
chondrocytes 1
Fgf8 (Rattus norvegicus)
GAG (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 38 98.80 Very High Very High Very High
metalloproteinase 8 93.52 High High
Inflammation 7 77.52 Quite High
Arthritis 15 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 39 98.80 Very High Very High Very High
INFLAMMATION 8 77.52 Quite High
Disease Progression 1 61.12 Quite High
Injury 5 51.68 Quite High
Arthritis 15 20.68 Low Low
Pain 5 5.00 Very Low Very Low Very Low
Hyperplasia 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our study, FGF8 induced the production of proMMP-3 and significantly decreased the residual amount of S-GAG in the ECM in cultured chondrocytes.
FGF8 Positive_regulation (induced) of GAG in chondrocytes
1) Confidence 0.55 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575604 Disease Relevance 0.48 Pain Relevance 0.23

General Comments

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