INT250932

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL1B, BDNF) cytosol (IL1B) signal transduction (IL1B)
extracellular space (IL1B) aging (IL1B) cytoplasmic membrane-bounded vesicle (BDNF)
IL1B (Homo sapiens)
BDNF (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 32 100.00 Very High Very High Very High
Neuropeptide 20 100.00 Very High Very High Very High
substance P 26 98.40 Very High Very High Very High
Pain 28 92.12 High High
Nerve growth factor 108 89.92 High High
Pyramidal cell 4 64.52 Quite High
backache 6 5.00 Very Low Very Low Very Low
Chronic low back pain 4 5.00 Very Low Very Low Very Low
Dorsal horn 4 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 22 92.12 High High
Disease 20 75.08 Quite High
Intervertebral Disk Degeneration 8 27.96 Quite Low
Nociception 12 25.00 Low Low
Low Back Pain 10 5.00 Very Low Very Low Very Low
Osteoarthritis 6 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Inflammatory Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, modulation of neurotrophin expression by IL-1?
IL-1 Regulation (modulation) of Gene_expression (expression) of neurotrophin
1) Confidence 0.06 Published 2008 Journal Arthritis Res Ther Section Abstract Doc Link PMC2575613 Disease Relevance 0.17 Pain Relevance 0.36
To examine the effect of disc-related proinflammatory cytokines on neurotrophin and neuropeptide expression in the IVD, cells derived from non-degenerate and degenerate NP patient samples were treated with either IL-1?
IL-1 Spec (examine) Regulation (effect) of Gene_expression (expression) of neurotrophin associated with neuropeptide and cytokine
2) Confidence 0.06 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575613 Disease Relevance 0.08 Pain Relevance 0.34

General Comments

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