INT250934

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.62
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (BDNF, NGF) endosome (NGF) signal transduction (NGF)
extracellular space (NGF) cytoplasmic membrane-bounded vesicle (BDNF)
BDNF (Homo sapiens)
NGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 122 100.00 Very High Very High Very High
substance P 26 100.00 Very High Very High Very High
Neurotransmitter 1 93.28 High High
nociceptor 1 80.56 Quite High
Lasting pain 2 76.32 Quite High
Inflammation 5 74.16 Quite High
cytokine 36 73.28 Quite High
backache 7 65.00 Quite High
Pain 31 60.00 Quite High
neurotrophin 3 3 59.68 Quite High
Disease Link Frequency Relevance Heat
Nociception 17 90.08 High High
Pain 29 75.44 Quite High
INFLAMMATION 5 74.16 Quite High
Low Back Pain 11 65.00 Quite High
Intervertebral Disk Degeneration 10 62.08 Quite High
Disease 21 5.00 Very Low Very Low Very Low
Osteoarthritis 6 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Inflammatory Pain 4 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Quantitative real-time PCR was carried out using the predesigned FAM MGB combined primer and the probe sets termed assays on demand for NGF, BDNF and substance P from Applied Biosystems (Warrington, UK): NGF, Hs00171458_m1; BDNF, Hs00542425_s1; substance P, Hs00243225_m1.
BDNF Binding (demand) of NGF associated with nerve growth factor and substance p
1) Confidence 0.39 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575613 Disease Relevance 0 Pain Relevance 0.34
Quantitative real-time PCR was carried out using the predesigned FAM MGB combined primer and the probe sets termed assays on demand for NGF, BDNF and substance P from Applied Biosystems (Warrington, UK): NGF, Hs00171458_m1; BDNF, Hs00542425_s1; substance P, Hs00243225_m1.
BDNF Binding (demand) of NGF associated with nerve growth factor and substance p
2) Confidence 0.34 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575613 Disease Relevance 0 Pain Relevance 0.34
In addition to NGF, BDNF has recognized neuroprotective effects [21].
BDNF Binding (recognized) of NGF associated with nerve growth factor
3) Confidence 0.33 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575628 Disease Relevance 0.62 Pain Relevance 0.67

General Comments

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