INT251099

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Context Info
Confidence 0.43
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.06
Pain Relevance 1.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Calm1) nucleoplasm (Calm1) cytoskeleton (Calm1)
cell cycle (Calm1) cellular_component (Calm1) biological_process (Calm1)
Anatomy Link Frequency
knee 3
cartilage 2
hip 1
Calm1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
complementary and alternative medicine 144 100.00 Very High Very High Very High
Osteoarthritis 144 99.32 Very High Very High Very High
Arthritis 11 65.92 Quite High
Multiple sclerosis 185 55.36 Quite High
Acupuncture 7 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
cannabis 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 141 99.32 Very High Very High Very High
Chronic Disease 22 76.80 Quite High
Adhesions 3 74.12 Quite High
Arthritis 8 65.92 Quite High
Cancer 7 62.08 Quite High
Disease 66 61.12 Quite High
Demyelinating Disease 190 55.36 Quite High
Knee Osteoarthritis 3 50.00 Quite Low
Arthropathy 6 42.16 Quite Low
Obesity 7 32.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the Norwegian context, a recent study among the general population shows that, “over the previous 12 months”, 48.7% of the respondents had received CAM by CAM practitioners outside of or by health care personnel inside the health care system.
Positive_regulation (received) of Gene_expression (practitioners) of CAM associated with complementary and alternative medicine
1) Confidence 0.43 Published 2010 Journal International Journal of Qualitative Studies on Health and Well-being Section Body Doc Link PMC2900149 Disease Relevance 0.26 Pain Relevance 0.63
The well clarified role Ca2+-calmodulin signal played in chondrogenesis and normal cartilage phenotype maintaining, together with the results of the microarray analysis [7] showing higher levels of CALM1 expression both in hip and knee OA, have interested us in assessing whether this genetic polymorphism is also associated with OA in a Chinese Han population.
Positive_regulation (levels) of Gene_expression (expression) of CALM1 in knee associated with osteoarthritis
2) Confidence 0.43 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2576056 Disease Relevance 0.56 Pain Relevance 0.25
In addition, higher levels of CALM1 expression in hip and knee OA cartilage than in normal were also observed [7].
Positive_regulation (levels) of Gene_expression (expression) of CALM1 in cartilage associated with osteoarthritis
3) Confidence 0.43 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2576056 Disease Relevance 0.67 Pain Relevance 0.30
The well clarified role Ca2+-calmodulin signal played in chondrogenesis and normal cartilage phenotype maintaining, together with the results of the microarray analysis [7] showing higher levels of CALM1 expression both in hip and knee OA, have interested us in assessing whether this genetic polymorphism is also associated with OA in a Chinese Han population.
Positive_regulation (levels) of in hip Gene_expression (expression) of CALM1 in knee associated with osteoarthritis
4) Confidence 0.15 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2576056 Disease Relevance 0.56 Pain Relevance 0.25

General Comments

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