INT251112

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.04
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CYP17A1) small molecule metabolic process (CYP17A1) endoplasmic reticulum (CYP17A1)
CYP17A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 10 5.00 Very Low Very Low Very Low
iatrogenic 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Catecholamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adrenal Cancer 274 99.52 Very High Very High Very High
Obesity 14 85.20 High High
Osteoporosis 6 78.64 Quite High
Hepatotoxicity 1 67.00 Quite High
Insulin Resistance 6 60.24 Quite High
Congenital Anomalies 3 59.04 Quite High
Polycystic Ovary Syndrome 28 56.96 Quite High
Testosterone Deficiency 2 50.00 Quite Low
Disorder Of Lipid Metabolism 1 43.92 Quite Low
Diabetes Mellitus 14 30.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, while the 17,20-lyase activity of P450c17 towards ?
Negative_regulation (while) of Gene_expression (activity) of P450c17
1) Confidence 0.24 Published 2010 Journal International Journal of Pediatric Endocrinology Section Body Doc Link PMC2910408 Disease Relevance 0.81 Pain Relevance 0
Finally, while the 17,20-lyase activity of P450c17 towards ?
Negative_regulation (while) of Gene_expression (activity) of 17,20-lyase
2) Confidence 0.21 Published 2010 Journal International Journal of Pediatric Endocrinology Section Body Doc Link PMC2910408 Disease Relevance 0.80 Pain Relevance 0
PGZ but not RGZ inhibited the expression of the CYP17 and HSD3B2 genes.
Negative_regulation (inhibited) of Gene_expression (expression) of CYP17
3) Confidence 0.17 Published 2008 Journal Cardiovasc Diabetol Section Body Doc Link PMC2576082 Disease Relevance 0.43 Pain Relevance 0

General Comments

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