INT251115

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (AR, Ctnnb1) nucleus (AR, Ctnnb1) enzyme binding (AR, Ctnnb1)
cytoplasm (AR, Ctnnb1) cell proliferation (AR, Ctnnb1) transcription factor binding (AR, Ctnnb1)
Anatomy Link Frequency
nucleus 2
AR (Homo sapiens)
Ctnnb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 1 88.88 High High
Angina 1 80.72 Quite High
Inflammation 1 25.16 Quite Low
agonist 1 5.00 Very Low Very Low Very Low
Catecholamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 8 99.92 Very High Very High Very High
Depression 1 88.88 High High
Coronary Artery Disease 4 85.92 High High
Cv General 3 Under Development 1 80.72 Quite High
Neuropathic Pain 1 65.80 Quite High
Hyperlipidemia 1 62.08 Quite High
Congenital Anomalies 1 59.92 Quite High
Diabetes Mellitus 14 55.64 Quite High
Increased Venous Pressure Under Development 1 53.68 Quite High
Testosterone Deficiency 2 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
They also showed that T inhibited adipogenic differentiation of pre-adipocytes by activation of androgen receptor (AR)/beta-catenin interaction and translocation of androgen receptor/beta catenin complex to the nucleus, thus bypassing canonical Wnt signalling.
Positive_regulation (activation) of AR Binding (interaction) of beta-catenin in nucleus associated with obesity
1) Confidence 0.01 Published 2008 Journal Cardiovasc Diabetol Section Body Doc Link PMC2576082 Disease Relevance 1.02 Pain Relevance 0.13

General Comments

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