INT251127

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.49
Pain Relevance 2.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dlg2) cytoplasm (Dlg2)
Dlg2 (Mus musculus)
Pain Link Frequency Relevance Heat
narcan 12 99.84 Very High Very High Very High
withdrawal 46 99.16 Very High Very High Very High
Morphine 154 98.68 Very High Very High Very High
Central nervous system 22 98.52 Very High Very High Very High
Physical dependence 30 96.32 Very High Very High Very High
tolerance 50 95.36 Very High Very High Very High
Lasting pain 16 94.44 High High
Glutamate receptor 2 86.88 High High
potassium channel 2 85.64 High High
Dorsal horn 24 80.88 Quite High
Disease Link Frequency Relevance Heat
Substance Withdrawal Syndrome 8 99.16 Very High Very High Very High
Targeted Disruption 102 99.12 Very High Very High Very High
Drug Dependence 30 96.32 Very High Very High Very High
Pain 36 94.44 High High
INFLAMMATION 4 68.76 Quite High
Hyperalgesia 6 44.36 Quite Low
Neuropathic Pain 6 43.36 Quite Low
Cerebellar Diseases 2 29.44 Quite Low
Hypersensitivity 6 5.00 Very Low Very Low Very Low
Pathologic Processes 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, the present study was the first to demonstrate that PSD-93 deletion has distinct effects on synaptic NMDAR expression in the CNS.
Regulation (effects) of Gene_expression (deletion) of PSD-93 associated with central nervous system
1) Confidence 0.35 Published 2008 Journal Mol Pain Section Body Doc Link PMC2576175 Disease Relevance 0.79 Pain Relevance 1.28
Effect of PSD-93 deletion on naloxone-induced withdrawal symptoms
Regulation (Effect) of Gene_expression (deletion) of PSD-93 associated with narcan and withdrawal
2) Confidence 0.35 Published 2008 Journal Mol Pain Section Body Doc Link PMC2576175 Disease Relevance 0.70 Pain Relevance 0.94

General Comments

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