INT251143

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Context Info
Confidence 0.22
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin2b) plasma membrane (Grin2b) embryo development (Grin2b)
cytoplasm (Dlg3)
Grin2b (Mus musculus)
Dlg3 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 11 96.44 Very High Very High Very High
Hippocampus 3 91.20 High High
Spinal cord 8 84.96 Quite High
Pain 6 81.20 Quite High
Dorsal horn 12 75.84 Quite High
Dorsal horn neuron 1 70.60 Quite High
Morphine 77 50.00 Quite Low
tolerance 25 50.00 Quite Low
Physical dependence 15 50.00 Quite Low
withdrawal 23 20.72 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 51 85.68 High High
Pain 18 81.20 Quite High
Drug Dependence 15 50.00 Quite Low
Substance Withdrawal Syndrome 4 21.08 Low Low
Nervous System Injury 1 5.52 Low Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Pathologic Processes 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PSD-95 and SAP102, two members of the MAGUK family of proteins, also interact with NR2A and NR2B [13,32].
NR2B Binding (interact) of SAP102
1) Confidence 0.22 Published 2008 Journal Mol Pain Section Body Doc Link PMC2576175 Disease Relevance 0.32 Pain Relevance 0.55

General Comments

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