INT251224

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Context Info
Confidence 0.12
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.17
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Glyr1) nucleus (Glyr1) DNA binding (Glyr1)
cellular_component (Glyr1)
Glyr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 56 100.00 Very High Very High Very High
medulla 23 94.68 High High
Spinal cord 83 94.12 High High
midbrain 8 91.04 High High
agonist 6 82.28 Quite High
Central nervous system 17 67.36 Quite High
antagonist 8 53.68 Quite High
Pain 7 52.12 Quite High
Thalamus 6 42.72 Quite Low
Hippocampus 9 33.60 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 10 61.80 Quite High
Toxicity 1 55.44 Quite High
Pain 7 52.12 Quite High
Congenital Anomalies 1 28.28 Quite Low
Disease 3 20.32 Low Low
Tremor 2 14.72 Low Low
Spasticity 3 13.84 Low Low
Death 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Considerable advantages were provided by the apparent expression of only one type of GlyR (comprised of ?
Negative_regulation (type) of Gene_expression (expression) of GlyR
1) Confidence 0.12 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2889717 Disease Relevance 0.11 Pain Relevance 0.38
The amount of postsynaptic neurotransmitter receptor protein, such as NMDAR or GlyR, was not reduced (Table 1), which argues against a possible lack of postsynaptic sensitivity.
Neg (not) Negative_regulation (reduced) of Gene_expression (amount) of GlyR associated with neurotransmitter
2) Confidence 0.08 Published 2008 Journal Neural Develop Section Body Doc Link PMC2576228 Disease Relevance 0 Pain Relevance 0.13
The remaining GlyR subunit, ?
Negative_regulation (remaining) of Gene_expression (subunit) of GlyR
3) Confidence 0.02 Published 2010 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2866564 Disease Relevance 0.06 Pain Relevance 0.24

General Comments

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