INT251317

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Context Info
Confidence 0.37
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.69
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Limk1) nucleus (Limk1) kinase activity (Limk1)
cytoplasm (Limk1)
Limk1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 3 81.32 Quite High
Inflammatory response 27 74.88 Quite High
fibrosis 36 69.60 Quite High
Inflammation 99 65.52 Quite High
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 27 98.60 Very High Very High Very High
Glaucoma 12 95.80 Very High Very High Very High
Keloid Scars 24 93.80 High High
Corneal Opacity 3 92.40 High High
Cataract 3 91.04 High High
Proliferative Vitreoretinopathy 3 90.48 High High
Fibrosis 42 83.04 Quite High
Injury 42 82.16 Quite High
INFLAMMATION 87 74.88 Quite High
Ocular & Orbital Inflammation 39 57.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The links between LIMK1 and transcriptional pathways regulated by TGF-?
LIMK1 Binding (links) of
1) Confidence 0.37 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 0.29 Pain Relevance 0
A direct association between LIMK1 and bone morphogenetic protein receptor type II (BMPR-II), a member of the TGF-?
LIMK1 Binding (association) of
2) Confidence 0.37 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 1.05 Pain Relevance 0.13
Alternatively, LIMK1 could also act directly on transcriptional pathways given the facts that LIMK1 possesses two LIM domains [33], which may bind DNA; and that there have been reports describing LIMK1 nuclear localization [34] and its direct effects on the protein expression [35].
LIMK1 Binding (bind) of
3) Confidence 0.36 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 0.35 Pain Relevance 0.10

General Comments

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