INT251322

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Context Info
Confidence 0.50
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.05
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Limk1) nucleus (Limk1) kinase activity (Limk1)
cytoplasm (Limk1)
Limk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 27 99.68 Very High Very High Very High
Inflammation 99 92.64 High High
fibrosis 36 90.04 High High
cytokine 3 83.76 Quite High
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 87 99.68 Very High Very High Very High
Fibrosis 42 90.04 High High
Ocular & Orbital Inflammation 39 89.52 High High
Death 3 79.68 Quite High
Keloid Scars 24 76.40 Quite High
Injury 42 69.64 Quite High
Proliferative Vitreoretinopathy 3 67.20 Quite High
Glaucoma 12 66.92 Quite High
Cataract 3 64.24 Quite High
Corneal Opacity 3 62.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LIMK1 siRNA sequences
Positive_regulation (sequences) of LIMK1
1) Confidence 0.50 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 0.17 Pain Relevance 0.03
The important role of LIMK1 during inflammatory response and its possible cross-talk with TGF-?
Positive_regulation (role) of LIMK1 associated with inflammatory response
2) Confidence 0.50 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 1.32 Pain Relevance 0.39
LIMK1 is activated via phosphorylation by downstream effectors of small GTPases: Rho kinase (ROCK) [5]; p21 protein (Cdc42/Rac)-activated kinase (PAK1) [6]; and PAK4 [7].
Positive_regulation (activated) of LIMK1
3) Confidence 0.47 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 0.56 Pain Relevance 0.13

General Comments

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