INT251325

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.62
First Reported 2008
Last Reported 2008
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.30
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Limk1) nucleus (Limk1) kinase activity (Limk1)
cytoplasm (Limk1)
Anatomy Link Frequency
fibroblasts 2
Limk1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 48 91.20 High High
Inflammation 132 90.68 High High
Inflammatory response 36 31.52 Quite Low
cytokine 4 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 36 99.68 Very High Very High Very High
Injury 56 99.20 Very High Very High Very High
Fibrosis 56 91.20 High High
Ocular & Orbital Inflammation 52 90.68 High High
Stress 12 87.44 High High
INFLAMMATION 116 56.64 Quite High
Keloid Scars 32 5.00 Very Low Very Low Very Low
Glaucoma 16 5.00 Very Low Very Low Very Low
Cataract 4 5.00 Very Low Very Low Very Low
Proliferative Vitreoretinopathy 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The influence of LIMK1 downregulation on TGF-?
Regulation (influence) of Negative_regulation (downregulation) of LIMK1
1) Confidence 0.62 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 0.37 Pain Relevance 0
As actin cytoskeleton dynamics and cell adhesion to the ECM are crucially involved in cell migration [27], we investigated whether actin dynamics and focal adhesion formation were affected upon downregulation of LIMK1.
Spec (whether) Regulation (affected) of Spec (whether) Negative_regulation (downregulation) of LIMK1 associated with adhesions
2) Confidence 0.62 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 0.92 Pain Relevance 0.09
A scratch wound closure assay was used to test whether downregulation of LIMK1 would affect corneal fibroblasts motility.
Spec (whether) Regulation (affect) of Spec (whether) Negative_regulation (downregulation) of LIMK1 in fibroblasts associated with injury
3) Confidence 0.45 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2576479 Disease Relevance 0.41 Pain Relevance 0
The effects of LIMK1 downregulation on actin cytoskeleton organization and focal adhesion formation were studied.
Regulation (effects) of Negative_regulation (downregulation) of LIMK1 associated with adhesions
4) Confidence 0.27 Published 2008 Journal Molecular Vision Section Abstract Doc Link PMC2576479 Disease Relevance 0.61 Pain Relevance 0.21

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox