INT251358

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Context Info
Confidence 0.54
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.97
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cdh2) plasma membrane (Cdh2) protein complex (Cdh2)
Anatomy Link Frequency
cleavage 2
Cdh2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 2 56.96 Quite High
sodium channel 11 5.00 Very Low Very Low Very Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Nav1.6 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Nav1.1 1 5.00 Very Low Very Low Very Low
Action potential 1 5.00 Very Low Very Low Very Low
nav1.3 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dilated Cardiomyopathy 6 99.12 Very High Very High Very High
Adhesions 23 98.64 Very High Very High Very High
Heart Rate Under Development 3 96.48 Very High Very High Very High
Myocardial Infarction 4 89.92 High High
Stress 2 75.60 Quite High
Sprains And Strains 1 60.16 Quite High
Cardiomyopathy 5 26.40 Quite Low
Disease 2 8.80 Low Low
Cleidocranial Dysplasia 7 5.00 Very Low Very Low Very Low
Syndrome 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In general, E-cadherin is already expressed during the cleavage stage, while N-cadherin is induced later.
Positive_regulation (induced) of N-cadherin in cleavage
1) Confidence 0.54 Published 2008 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2576505 Disease Relevance 0 Pain Relevance 0.03
In general, E-cadherin is a basic cell adhesion factor that is already functioning during the cleavage period, and N-cadherin is induced during the formation of certain organs.
Positive_regulation (induced) of N-cadherin in cleavage associated with adhesions
2) Confidence 0.54 Published 2008 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2576505 Disease Relevance 0.34 Pain Relevance 0
In response to dilated cardiomyopathy (DCM) and congestive failure, there is a marked upregulation of adherens junction constituents, including N-cadherin, and ?
Positive_regulation (upregulation) of N-cadherin associated with dilated cardiomyopathy
3) Confidence 0.20 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2868981 Disease Relevance 0.63 Pain Relevance 0

General Comments

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