INT25137

Context Info Confidence 0.40 First Reported 1989 Last Reported 1989 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.21 Pain Relevance 0.14

signal transduction (Gnat3) GTPase activity (Gnat3) cytoplasm (Gnat3) signal transducer activity (Gnat3)

Anatomy Link Frequency plasma 2 Gnat3 (Mus musculus)

Pain Link Frequency Relevance Heat Angina 2 96.04 tolerance 1 80.56

Disease Link Frequency Relevance Heat Cv General 3 Under Development 2 96.04 Pressure Volume 2 Under Development 1 60.88 Heart Rate Under Development 1 57.44

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This patch provides a biphasic GTN release profile with therapeutic GTN plasma concentrations developing soon after application and persisting for 12h, but with low plasma concentrations during the remainder of the 24h period.

Positive_regulation (provides) of Localization (release) of GTN in plasma

1) Confidence 0.40 Published 1989 Journal Eur. Heart J. Section Abstract Doc Link 2501094 Disease Relevance 0.21 Pain Relevance 0.14

General Comments

This test has worked.