INT25141

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Context Info
Confidence 0.41
First Reported 1981
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 1.27
Pain Relevance 1.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 1
Rt3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 16 98.44 Very High Very High Very High
anesthesia 7 98.16 Very High Very High Very High
ischemia 3 96.84 Very High Very High Very High
Bile 8 89.76 High High
imagery 2 76.08 Quite High
Angina 1 68.32 Quite High
Disease Link Frequency Relevance Heat
Coronary Artery Disease 4 96.84 Very High Very High Very High
Syndrome 2 96.24 Very High Very High Very High
Stress 9 82.12 Quite High
Dyskinesias 1 81.48 Quite High
Hypokinesia 2 80.48 Quite High
Angina 1 68.32 Quite High
Metabolic Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was concluded that the administration of salicylate results in an immediate displacement of T4 and T3 from plasma protein binding and possibly inhibits the conversion of T4 to T3 and of rT3 to 3,3'-diiodothyronine which results in an increase of rT3 level in plasma.
Positive_regulation (increase) of rT3 in plasma
1) Confidence 0.41 Published 1981 Journal Horm. Metab. Res. Section Abstract Doc Link 7298011 Disease Relevance 0 Pain Relevance 0.07
When 5 mg linoleic acid was added to 1.2 ml ethanol, the increase of rT3 was significantly higher than that after ethanol only and, in addition, significant increase of 3',5'-T2 excretion was found.
Positive_regulation (increase) of rT3
2) Confidence 0.41 Published 1988 Journal Horm. Metab. Res. Section Abstract Doc Link 3397033 Disease Relevance 0 Pain Relevance 0.17
In addition, the level of rT3 in serum was significantly increased at 9 h after a single dose of 3.0 mg kg-1 DEX and after 5 days administration of 1.5 and 3.0 mg kg-1 DEX.
Positive_regulation (increased) of rT3 associated with dexamethasone
3) Confidence 0.21 Published 1985 Journal Endocrinol. Exp. Section Abstract Doc Link 3878778 Disease Relevance 0 Pain Relevance 0.50
With contrast-enhanced RT3DE, agreement increased to 95 of 108 coronary territories (88%, kappa = 0.59).
Positive_regulation (increased) of RT3DE
4) Confidence 0.20 Published 2007 Journal Am. J. Cardiol. Section Abstract Doc Link 17223433 Disease Relevance 0.98 Pain Relevance 0.26
In another experiment a decrease of T3 excretion was observed together with an increase of rT3 excretion and of T4/T3 and rT3/T3 ratio between 9 and 11 h after a single injection of 0.75, 1.5 and 3.0 mg kg-1 DEX, the differences being in most cases significant as compared to controls.
Positive_regulation (increase) of rT3 associated with dexamethasone
5) Confidence 0.06 Published 1985 Journal Endocrinol. Exp. Section Abstract Doc Link 3878778 Disease Relevance 0 Pain Relevance 0.47
Interestingly, there was a tendency for rT3 to increase and it reach its highest value 24h postoperatively with the difference being statistically significant (p<0.05).
Positive_regulation (increase) of rT3
6) Confidence 0.03 Published 1998 Journal Endocr. Res. Section Abstract Doc Link 9738698 Disease Relevance 0.29 Pain Relevance 0
While serum cortisol, fT4, T4, rT3 levels increased, TBG, TSH, fT3 and T3 decreased.
Positive_regulation (increased) of rT3
7) Confidence 0.00 Published 1989 Journal Ital J Surg Sci Section Abstract Doc Link 2501233 Disease Relevance 0 Pain Relevance 0.17

General Comments

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