INT251418

Context Info Confidence 0.12 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

mitochondrion (Aldh2) signal transduction (Gnat3) oxidoreductase activity (Aldh2) GTPase activity (Gnat3) cytoplasm (Gnat3) signal transducer activity (Gnat3)

Gnat3 (Mus musculus) Aldh2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat tolerance 14 5.00 addiction 5 5.00 Angina 1 5.00

Disease Link Frequency Relevance Heat Increased Venous Pressure Under Development 2 5.00 Stress 1 5.00 Cv General 3 Under Development 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Inhibition of Dehydrogenase Activity by GTN—To study the inactivation of ALDH2 by GTN in real time we monitored the formation of NADH from NAD+ spectrophotometrically at 340 nm and determined how the activity of ALDH2 was affected by the addition of GTN.

GTN Regulation (affected) of ALDH2

1) Confidence 0.12 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2576553 Disease Relevance 0 Pain Relevance 0

General Comments

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