INT251423

Context Info Confidence 0.09 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

cytoplasm (Gnat3, Aldh3a1) aging (Aldh3a1) endoplasmic reticulum (Aldh3a1) GTPase activity (Gnat3) signal transducer activity (Gnat3) cytosol (Aldh3a1)

Gnat3 (Mus musculus) Aldh3a1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat addiction 5 8.64 tolerance 14 5.00 Angina 1 5.00

Disease Link Frequency Relevance Heat Increased Venous Pressure Under Development 2 5.00 Stress 1 5.00 Cv General 3 Under Development 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Inactivation and Reactivation of ALDH2-catalyzed GTN Reduction—To assess how GTN affects its own reduction by mitochondrial ALDH we measured GTN reductase activity, removed low molecular weight ingredients from the assay mixture by gel filtration, and repeated the activity assay with the recovered enzyme.

GTN Regulation (affects) of mitochondrial ALDH Binding (reduction) of

1) Confidence 0.09 Published 2008 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2576553 Disease Relevance 0 Pain Relevance 0

General Comments

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