INT251578

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF) extracellular space (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 6 97.20 Very High Very High Very High
Inflammation 20 85.68 High High
metalloproteinase 1 64.96 Quite High
Etanercept 7 12.04 Low Low
Adalimumab 4 10.88 Low Low
Infliximab 4 10.28 Low Low
Multiple sclerosis 19 5.00 Very Low Very Low Very Low
Central nervous system 10 5.00 Very Low Very Low Very Low
Glutamate 7 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 13 93.08 High High
INFLAMMATION 24 85.68 High High
Disease 51 5.00 Very Low Very Low Very Low
Demyelinating Disease 24 5.00 Very Low Very Low Very Low
Targeted Disruption 17 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 9 5.00 Very Low Very Low Very Low
Parkinson's Disease 7 5.00 Very Low Very Low Very Low
Death 7 5.00 Very Low Very Low Very Low
Injury 7 5.00 Very Low Very Low Very Low
Stroke 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thalidomide inhibits TNF through enhanced degradation of TNF mRNA [118,119], however is can also alter the expression of COX-2, IL-1?
Positive_regulation (enhanced) of Protein_catabolism (degradation) of TNF mRNA
1) Confidence 0.41 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2577641 Disease Relevance 0.26 Pain Relevance 0.16

General Comments

This test has worked.

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