INT251606

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Context Info
Confidence 0.73
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.26
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Msn) nucleolus (Msn) plasma membrane (Msn)
cytoskeleton (Msn) nucleus (Msn) cytoplasm (Msn)
Anatomy Link Frequency
spike 1
Msn (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 29 89.28 High High
tetrodotoxin 1 78.08 Quite High
Multiple sclerosis 22 73.76 Quite High
Neuritis 17 73.48 Quite High
Inflammation 43 71.76 Quite High
Glutamate receptor 1 64.12 Quite High
Demyelination 123 39.12 Quite Low
Central nervous system 35 35.04 Quite Low
Spinal cord 33 5.00 Very Low Very Low Very Low
Serotonin 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 68 95.84 Very High Very High Very High
Sprains And Strains 84 93.36 High High
Disorders Of Creatine Metabolism 1 86.00 High High
Demyelinating Disease 229 76.28 Quite High
Optic Neuritis 17 73.48 Quite High
INFLAMMATION 43 71.76 Quite High
Multiple Sclerosis 19 62.68 Quite High
Infection 70 42.16 Quite Low
Viral Meningitis 14 36.08 Quite Low
Viral Infection 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dimebon was added to the 14 DIV MSN at the final concentration of 5 ?
Protein_catabolism (added) of MSN
1) Confidence 0.73 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2577671 Disease Relevance 0.28 Pain Relevance 0.23
The ~1300 amino acid spike protein in MHV-A59 is usually posttranslationally cleaved into two domains which associate with each other to form a functional dimer.
Protein_catabolism (cleaved) of spike protein in spike
2) Confidence 0.01 Published 2010 Journal Interdisciplinary Perspectives on Infectious Diseases Section Body Doc Link PMC2905936 Disease Relevance 0.98 Pain Relevance 0.42

General Comments

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