INT25173

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Context Info
Confidence 0.17
First Reported 1989
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.59
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
brain 1
bile 1
H2-M3 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 11 93.20 High High
narcan 5 91.72 High High
withdrawal 1 80.36 Quite High
Opioid 1 75.00 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Sprains And Strains 7 97.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was a correlation between formation rate of M3G and N3G (r = 0.65 brain and r = 0.73 liver).
Localization (rate) of M3G in brain
1) Confidence 0.17 Published 1989 Journal Pain Section Abstract Doc Link 2506504 Disease Relevance 0.59 Pain Relevance 0.54
Loss of biliary M3G secretion in Mrp2(-/-) mice results in its increased sinusoidal transport that can be attributed to Mrp3.
Localization (secretion) of M3G
2) Confidence 0.05 Published 2007 Journal Mol. Pharmacol. Section Abstract Doc Link 17485564 Disease Relevance 0 Pain Relevance 0.26
Of the M3G and M6G formed during a single passage, 19 +/- 11% and 9 +/- 9%, respectively, was excreted into bile; the values were significantly different (P = 0.002).
Localization (excreted) of M3G in bile
3) Confidence 0.02 Published 1997 Journal Pharm. Res. Section Body Doc Link 9279882 Disease Relevance 0 Pain Relevance 0

General Comments

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