INT251745

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Context Info
Confidence 0.58
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.96
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (GATA1) nucleolus (GATA1) nucleus (GATA1)
DNA binding (GATA1) cell-cell signaling (GATA1)
GATA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 61 87.84 High High
cva 3 11.76 Low Low
Angina 3 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Headache 47 87.84 High High
Migraine Without Aura 7 83.96 Quite High
Migraine With Aura 18 81.16 Quite High
Diabetes Mellitus 4 72.88 Quite High
Coronary Artery Disease 18 71.32 Quite High
Disease 8 58.04 Quite High
Stroke 12 54.88 Quite High
Heart Defects 6 52.48 Quite High
Patent Foramen Ovale 30 47.36 Quite Low
Atherosclerosis 5 37.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Six family members of have been identified in vertebrates to be part of the GATA family and have been subdivided in two groups: GATA-1, GATA-2, and GATA-3, which are expressed in the hematopoetic system [19].
Gene_expression (expressed) of GATA-1
1) Confidence 0.58 Published 2008 Journal The Open Neurology Journal Section Body Doc Link PMC2577932 Disease Relevance 0.57 Pain Relevance 0.51
Having analysed data with TRANSFAC system, we may assume that the disturbed attachment of such factors as (C/EBP(CCAAT enhancer binding protein) Hoxa-3,Sp1 (serine protease inhibitor) or GATA-1, (GATA nucleotide sequence) may have an impact on IGF-1 protein synthesis, but we did not observed any significant correlation between promoter P1 polymorphism and serum IGF-1 levels.
Gene_expression (synthesis) of GATA-1
2) Confidence 0.08 Published 2010 Journal Protein J Section Body Doc Link PMC2992669 Disease Relevance 0.40 Pain Relevance 0

General Comments

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