INT251780

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.62
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (RRAD, MTOR) mitochondrion (MTOR) Golgi apparatus (MTOR)
endoplasmic reticulum (MTOR) GTPase activity (RRAD) cytoplasm (MTOR)
RRAD (Homo sapiens)
MTOR (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 4 28.32 Quite Low
Inflammation 5 5.00 Very Low Very Low Very Low
peripheral neuropathy 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Advanced Or Metastatic Breast Cancer 84 99.24 Very High Very High Very High
Cancer 35 93.00 High High
Breast Cancer 59 74.08 Quite High
Metastasis 4 40.40 Quite Low
Stomatitis 5 33.68 Quite Low
Fatigue 10 32.72 Quite Low
Appetite Loss 3 32.00 Quite Low
Diarrhoea 14 29.12 Quite Low
Headache 4 28.32 Quite Low
Exanthema 6 27.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RAD001 is a highly specific inhibitor of the mammalian target of rapamycin (mTOR), a large polypeptide kinase which forms part of the PI3K/Akt pathway.
RAD001 Negative_regulation (inhibitor) of mTOR
1) Confidence 0.00 Published 2008 Journal J Hematol Oncol Section Body Doc Link PMC2579406 Disease Relevance 0.62 Pain Relevance 0

General Comments

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