INT251811

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (IHH) extracellular space (IHH) extracellular region (IHH)
plasma membrane (IHH) cell-cell signaling (IHH)
Anatomy Link Frequency
chondrocyte 1
scleral cells 1
IHH (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 90.64 High High
Inflammation 4 27.60 Quite Low
Arthritis 6 25.04 Quite Low
anesthesia 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Focal Cartilage Defect 2 94.32 High High
Disease 6 48.56 Quite Low
Osteoarthritis 4 40.64 Quite Low
INFLAMMATION 4 27.60 Quite Low
Arthritis 6 25.04 Quite Low
Aging 2 8.48 Low Low
Myopia 6 5.00 Very Low Very Low Very Low
Scleral Diseases 6 5.00 Very Low Very Low Very Low
Degenerative Myopia 4 5.00 Very Low Very Low Very Low
Retinoblastoma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, other chondrocyte-associated genes, such as sox5, IHH, and PTHR1 were also up-regulated.
Positive_regulation (regulated) of IHH in chondrocyte
1) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2579486 Disease Relevance 0 Pain Relevance 0.05
After in vitro chondrogenesis of scleral cells, COL10A, SOX5, IHH, and MMP13 mRNA expressions increased.
Positive_regulation (increased) of IHH in scleral cells
2) Confidence 0.13 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2579486 Disease Relevance 0.09 Pain Relevance 0

General Comments

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