INT2519

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Context Info
Confidence 0.43
First Reported 1979
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 5.27
Pain Relevance 1.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
cavity 1
heart 1
VCF (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 2 100.00 Very High Very High Very High
anesthesia 4 99.24 Very High Very High Very High
Morphine 3 93.88 High High
cva 250 91.92 High High
Pain 16 85.20 High High
Thoracotomy 1 82.04 Quite High
Angina 1 72.56 Quite High
ischemia 2 70.96 Quite High
Analgesic 3 69.20 Quite High
backache 1 50.52 Quite High
Disease Link Frequency Relevance Heat
Compression Fractures 31 100.00 Very High Very High Very High
Depression 2 100.00 Very High Very High Very High
Stress 4 98.36 Very High Very High Very High
Kyphosis 7 96.12 Very High Very High Very High
Deep Vein Thrombosis 238 91.92 High High
Coronary Artery Disease 6 90.76 High High
Pulmonary Embolism 111 88.92 High High
Death 36 88.16 High High
Congenital Anomalies 1 85.84 High High
Pain 14 85.20 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since anesthesia produced regional difference in the degree of depression of VCF, we conclude that anesthesia will produce patterns of ventricular contraction which are variable and unpredictable.
Negative_regulation (depression) of VCF associated with anesthesia and depression
1) Confidence 0.43 Published 1979 Journal Jpn Heart J Section Abstract Doc Link 459103 Disease Relevance 0.10 Pain Relevance 0.38
Velocity of circumferential fiber shortening (Vcf), normalized for heart rate and preload, was significantly lower in the anaesthetised dogs (0.63 +/- 0.22 circ/sec vs 0.89 +/- 0.26 circ/sec, p less than 0.05); this decline in Vcf, in association with a lower systolic wall stress (85 +/- 29 10(3) dynes/cm2 vs 119 +/- 23 10(3) dynes/cm2, p less than 0.05) indicates that thiopental-morphine anaesthesia depresses contractility.
Negative_regulation (decline) of Vcf in heart associated with stress and morphine
2) Confidence 0.37 Published 1990 Journal Clin Invest Med Section Abstract Doc Link 2311313 Disease Relevance 0.17 Pain Relevance 0.23
The mean Vcf was slightly and not significantly reduced, while early-systolic and end-diastolic stress and the constant of stiffness consistently increased in both groups.
Neg (not) Negative_regulation (reduced) of Vcf associated with stress
3) Confidence 0.37 Published 1983 Journal Int. J. Cardiol. Section Abstract Doc Link 6874144 Disease Relevance 0.95 Pain Relevance 0.18
With this technique, reduction of VCF is achieved by a transpedicular intracorporal balloon expansion and retention by PMMA cement augmentation [9].
Negative_regulation (reduction) of VCF associated with compression fractures
4) Confidence 0.37 Published 2008 Journal Patient Saf Surg Section Body Doc Link PMC2248169 Disease Relevance 1.27 Pain Relevance 0.31
CONCLUSION: A gradual decrease of BME in osteoporotic VCF treated with PV is apparent during 12 months of MR imaging follow-up.
Negative_regulation (decrease) of VCF
5) Confidence 0.36 Published 2006 Journal AJNR Am J Neuroradiol Section Body Doc Link 16687528 Disease Relevance 0.19 Pain Relevance 0
Kyphoplasty is a new technique, which introduces a balloon into the vertebral body transpedicularly to reduce the VCF while creating a cavity for the cement injection.
Negative_regulation (reduce) of VCF in cavity
6) Confidence 0.34 Published 2003 Journal Eur Spine J Section Abstract Doc Link 14505122 Disease Relevance 0.51 Pain Relevance 0.23
In our base case analysis, we did not account for removal of VCF, which at our facility (Foothills Medical Centre) costs Can$1,300 (Table 3).
Negative_regulation (removal) of VCF
7) Confidence 0.32 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2695771 Disease Relevance 1.13 Pain Relevance 0.22
Removal of the VCF upon discharge from hospital added Can$637 to the VCF strategy.


Negative_regulation (Removal) of VCF
8) Confidence 0.32 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2695771 Disease Relevance 0.94 Pain Relevance 0.24

General Comments

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