INT25200

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Context Info
Confidence 0.05
First Reported 1989
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 13
Total Number 13
Disease Relevance 1.75
Pain Relevance 3.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (GPER) endoplasmic reticulum (GPER) plasma membrane (GPER)
signal transducer activity (GPER)
Anatomy Link Frequency
cochlear 6
blood 2
spinal 1
vasculature 1
sympathetic 1
GPER (Homo sapiens)
Pain Link Frequency Relevance Heat
epidural 2 100.00 Very High Very High Very High
qutenza 49 99.92 Very High Very High Very High
substance P 4 99.22 Very High Very High Very High
Neuropeptide 2 98.78 Very High Very High Very High
isoflurane 1 94.12 High High
Serotonin 4 92.76 High High
cytokine 4 90.40 High High
anesthesia 3 82.08 Quite High
agonist 2 81.92 Quite High
ketamine 1 81.64 Quite High
Disease Link Frequency Relevance Heat
Hypotension 5 100.00 Very High Very High Very High
Endolymphatic Hydrops 6 99.58 Very High Very High Very High
Hypoxia 1 99.52 Very High Very High Very High
Adhesions 21 98.12 Very High Very High Very High
Edema 6 89.28 High High
Coronary Stenosis 1 80.56 Quite High
Increased Venous Pressure Under Development 4 58.36 Quite High
Hypertrophy 1 36.72 Quite Low
Ganglion Cysts 2 25.00 Low Low
Cv Unclassified Under Development 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of feG on the binding of antibodies to cell surface markers that are related to cell migration and adhesion were examined.
Spec (examined) Positive_regulation (effect) of feG associated with adhesions
1) Confidence 0.05 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.54 Pain Relevance 0
Results demonstrated that EGb 761 partly counteracted sodium salicylate-induced decreases in cochlear blood flow (CBF) and enhanced CBF increases induced by hypoxia.
Positive_regulation (increases) of cochlear blood flow in cochlear associated with hypoxia
2) Confidence 0.01 Published 1996 Journal Eur Arch Otorhinolaryngol Section Abstract Doc Link 8932425 Disease Relevance 0.10 Pain Relevance 0.12
The peripheral and central effects of IL-6 are presumably mediated through its membrane receptor (IL-6R).
Positive_regulation (mediated) of membrane receptor
3) Confidence 0.00 Published 1999 Journal Neurochem. Res. Section Abstract Doc Link 10485589 Disease Relevance 0 Pain Relevance 0.30
Although certain studies have reported evoked changes in cochlear blood flow (CBF) with activation of the sympathetic fibers to the cochlear vasculature, other studies have failed to show evidence of sympathetic contribution to CBF regulation when the cervical sympathetic fibers were unilaterally sectioned.
Positive_regulation (activation) of cochlear blood flow in sympathetic
4) Confidence 0.00 Published 1997 Journal Hear. Res. Section Abstract Doc Link 9083811 Disease Relevance 0 Pain Relevance 0.05
Capsaicin has been previously shown to increase cochlear blood flow (CBF) in a dose-dependent manner.
Positive_regulation (increase) of cochlear blood flow in blood associated with qutenza
5) Confidence 0.00 Published 1996 Journal Hear. Res. Section Abstract Doc Link 8922985 Disease Relevance 0 Pain Relevance 0.35
Nitric oxide mediates capsaicin-induced increase in cochlear blood flow.
Positive_regulation (increase) of cochlear blood flow in cochlear associated with qutenza
6) Confidence 0.00 Published 1996 Journal Hear. Res. Section Title Doc Link 8922985 Disease Relevance 0.06 Pain Relevance 0.84
Effect of endolymphatic hydrops on capsaicin-evoked increase in cochlear blood flow.
Positive_regulation (increase) of cochlear blood flow in cochlear associated with endolymphatic hydrops and qutenza
7) Confidence 0.00 Published 1995 Journal Acta Otolaryngol. Section Title Doc Link 8749196 Disease Relevance 0.41 Pain Relevance 0.79
Capsaicin, which causes release of neuropeptides including substance P, has been shown to cause dose-related increases in cochlear blood flow (CBF).
Positive_regulation (increases) of cochlear blood flow in blood associated with qutenza, neuropeptide and substance p
8) Confidence 0.00 Published 1995 Journal Acta Otolaryngol. Section Abstract Doc Link 8749196 Disease Relevance 0.26 Pain Relevance 0.58
Electrically stimulated increases in cochlear blood flow: II.
Positive_regulation (increases) of cochlear blood flow in cochlear
9) Confidence 0.00 Published 1989 Journal Otolaryngol Head Neck Surg Section Title Doc Link 2508007 Disease Relevance 0 Pain Relevance 0.08
Capsaicin, the vanilloid that selectively activates vanilloid receptors (VRs) on sensory neurons for noxious perception, has been reported to increase cochlear blood flow (CBF).
Positive_regulation (increase) of cochlear blood flow in cochlear associated with qutenza
10) Confidence 0.00 Published 2003 Journal J. Neurophysiol. Section Abstract Doc Link 12660354 Disease Relevance 0 Pain Relevance 0.32
In a companion paper, we reported that electrical stimulation increased cochlear blood flow (CBF).
Positive_regulation (increased) of cochlear blood flow in cochlear
11) Confidence 0.00 Published 1989 Journal Otolaryngol Head Neck Surg Section Abstract Doc Link 2508007 Disease Relevance 0 Pain Relevance 0
To evaluate the effect of prostaglandin E1 (PGE1) or trimethaphan (TMP) induced hypotension on epidural blood flow (EBF) during spinal surgery, EBF was measured using the heat clearance method in 30 patients who underwent postero-lateral interbody fusion under isoflurane anaesthesia.
Positive_regulation (induced) of epidural blood flow in spinal associated with hypotension, epidural and isoflurane
12) Confidence 0.00 Published 1994 Journal Prostaglandins Leukot. Essent. Fatty Acids Section Abstract Doc Link 8022855 Disease Relevance 0.24 Pain Relevance 0.13
Coronary flow reserve (CFR) is the maximal increase in coronary blood flow (CBF) above its resting level for a given perfusion pressure when coronary vasculature is maximally dilated.
Positive_regulation (increase) of coronary blood flow in vasculature
13) Confidence 0.00 Published 2008 Journal Drugs Section Abstract Doc Link 18370439 Disease Relevance 0.14 Pain Relevance 0.10

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