INT252053

Context Info Confidence 0.08 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.34

peptidase activity (LTF) extracellular region (LTF) cytoplasm (LTF)

LTF (Homo sapiens)

Pain Link Frequency Relevance Heat Action potential 12 99.38 hyperexcitability 9 61.84 Neuronal excitability 25 16.12 Glutamate 40 5.00 Glutamate receptor 5 5.00 potassium channel 3 5.00 sodium channel 2 5.00 Neurotransmitter 2 5.00 tetrodotoxin 1 5.00 agonist 1 5.00

Disease Link Frequency Relevance Heat Epilepsy 8 5.00 Neurological Disease 6 5.00 Schizophrenia 4 5.00 Autism 3 5.00 Apoptosis 3 5.00 Anxiety Disorder 3 5.00 Convulsion 2 5.00 Ganglion Cysts 2 5.00 Neurofibromatosis 2 5.00 Lymphatic System Cancer 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Several lines of evidence suggested that these supernumerary action potentials arose in motor axons and were responsible for the increased transmitter release underlying LTF.

Regulation (responsible) of Localization (release) of LTF associated with action potential

1) Confidence 0.08 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2581892 Disease Relevance 0 Pain Relevance 0.34

General Comments

This test has worked.