INT252125

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Context Info
Confidence 0.27
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Snap25) plasma membrane (Snap25) cytoplasm (Snap25)
Anatomy Link Frequency
nervous system 2
Snap25 (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 2 60.40 Quite High
Neuropeptide 7 41.40 Quite Low
Hippocampus 5 39.92 Quite Low
Cholecystokinin 6 5.00 Very Low Very Low Very Low
Eae 6 5.00 Very Low Very Low Very Low
Pyramidal cell 2 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 5 96.60 Very High Very High Very High
Anxiety Disorder 4 85.72 High High
Convulsion 13 84.12 Quite High
Cognitive Disorder 7 5.00 Very Low Very Low Very Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Body Weight 4 5.00 Very Low Very Low Very Low
Tremor 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our present findings using genetic elimination of SNAP-25b suggest that even small alterations in the regulation of the Snap25 gene, resulting in a disturbed balance between SNAP-25a and SNAP-25b, lead to nervous system dysfunction.



Regulation (alterations) of Regulation (regulation) of Snap25 in nervous system
1) Confidence 0.27 Published 2008 Journal PLoS Genetics Section Abstract Doc Link PMC2581893 Disease Relevance 0.36 Pain Relevance 0.03

General Comments

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