INT252166

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 2.42
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Cdr1 (Mus musculus)
Pain Link Frequency Relevance Heat
cva 118 98.92 Very High Very High Very High
antidepressant 1 89.48 High High
depression 2 61.24 Quite High
imagery 42 50.00 Quite Low
positron emission tomography 16 49.68 Quite Low
Pain 15 34.52 Quite Low
Sciatica 7 15.20 Low Low
Hippocampus 8 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Embolism 110 98.92 Very High Very High Very High
Sprains And Strains 168 88.72 High High
Embolism 10 80.24 Quite High
Fungal Infection 18 76.92 Quite High
Attention Deficit Hyperactivity Disorder 12 75.12 Quite High
Cognitive Disorder 4 62.40 Quite High
Depression 2 61.24 Quite High
Phobia 1 52.92 Quite High
Infection 42 52.40 Quite High
Alzheimer's Dementia 34 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FSU ROM decreased right after CDR and returned to preoperative ROM in 1 month.
Negative_regulation (decreased) of CDR
1) Confidence 0.17 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628079 Disease Relevance 0 Pain Relevance 0
The prevalence of PE among patients with an unlikely clinical probability decreased with a decreasing CDR-cut-off value, ranging from 12.0% in patients with a Wells score ?
Negative_regulation (decreased) of CDR associated with cva
2) Confidence 0.10 Published 2010 Journal BMC Fam Pract Section Body Doc Link PMC2944151 Disease Relevance 0.69 Pain Relevance 0.31
The prevalence of PE among patients with an unlikely clinical probability decreased with a decreasing CDR-cut-off value, ranging from 12.0% in patients with a Wells score ?
Negative_regulation (decreasing) of CDR associated with cva
3) Confidence 0.10 Published 2010 Journal BMC Fam Pract Section Body Doc Link PMC2944151 Disease Relevance 0.69 Pain Relevance 0.30
Each of these genes can be upregulated in C. glabrata clinical isolates and disruption of CgCDR1 or CgCDR1/CgCDR2 leads to hypersusceptibility to fluconazole, cycloheximide, and chloramphenicol [4],[9],[10],[12],[13].
Negative_regulation (disruption) of CgCDR1
4) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2607542 Disease Relevance 0.25 Pain Relevance 0
Disruption of CgPDR1 in both azole-susceptible and azole-resistant isolates led to a drastic increase of azole susceptibility and to the complete downregulation of both CgCDR genes (Figure 5A and 5B), thus confirming the involvement of CgPdr1p in azole resistance.
Negative_regulation (downregulation) of CgCDR
5) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2607542 Disease Relevance 0.36 Pain Relevance 0
Each of these genes can be upregulated in C. glabrata clinical isolates and disruption of CgCDR1 or CgCDR1/CgCDR2 leads to hypersusceptibility to fluconazole, cycloheximide, and chloramphenicol [4],[9],[10],[12],[13].
Negative_regulation (disruption) of CgCDR1
6) Confidence 0.01 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2607542 Disease Relevance 0.25 Pain Relevance 0
The 52-week decline in patients on placebo on the ADAS-Cog, MMSE, CDR and ADCS-ADL was 8.2, 2.0, 0.5 and 5.1 points, respectively.
Negative_regulation (decline) of CDR
7) Confidence 0.01 Published 2008 Journal Journal of Neurology, Neurosurgery, and Psychiatry Section Body Doc Link PMC2582338 Disease Relevance 0.18 Pain Relevance 0.08

General Comments

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