INT2522

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Context Info
Confidence 0.11
First Reported 1979
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 0.71
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
polymorphonuclear leukocyte 1
ARSH (Homo sapiens)
Pain Link Frequency Relevance Heat
isoflurane 3 97.88 Very High Very High Very High
anesthesia 2 77.28 Quite High
cINOD 1 70.96 Quite High
Inflammation 3 57.76 Quite High
Chronic pancreatitis 22 22.20 Low Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 112 98.64 Very High Very High Very High
Cancer 20 86.32 High High
INFLAMMATION 4 70.56 Quite High
Skin Cancer 4 69.48 Quite High
Pancreatitis 22 22.20 Low Low
Ovarian Cancer 10 5.00 Very Low Very Low Very Low
Metastasis 6 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Liver Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upon transfection, sulfatase activity was most prominently increased in clone sulf-38 (Figure 3 D).
Positive_regulation (increased) of sulfatase
1) Confidence 0.11 Published 2005 Journal Mol Cancer Section Body Doc Link PMC1087876 Disease Relevance 0 Pain Relevance 0
Stable transfection of the Hsulf-1 negative Panc-1 pancreatic cancer cell line with a full length Hsulf-1 expression vector resulted in increased sulfatase activity and decreased cell-surface heparan-sulfate proteoglycan (HSPG) sulfation.
Positive_regulation (increased) of sulfatase associated with pancreatic cancer
2) Confidence 0.11 Published 2005 Journal Mol Cancer Section Abstract Doc Link PMC1087876 Disease Relevance 0.64 Pain Relevance 0
Intraperitoneal administration of carrageenin-zymosan suspension into rats induced an increment of the free activity and its ratio of aryl sulfatase in the exudate and such was accompanied by protein exudation and polymorphonuclear leukocyte emigration.
Positive_regulation (induced) of aryl sulfatase in polymorphonuclear leukocyte
3) Confidence 0.06 Published 1979 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 459158 Disease Relevance 0.07 Pain Relevance 0.10
Sulfatase activity was increased more than 60% with anesthetics.
Positive_regulation (increased) of Sulfatase
4) Confidence 0.03 Published 1997 Journal Gen. Pharmacol. Section Abstract Doc Link 9147027 Disease Relevance 0 Pain Relevance 0.29

General Comments

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