INT252220

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cpt1a) mitochondrion (Cpt1a) transferase activity, transferring acyl groups (Cpt1a)
lipid metabolic process (Cpt1a)
Cpt1a (Mus musculus)
Pain Link Frequency Relevance Heat
Catecholamine 12 95.56 Very High Very High Very High
agonist 14 84.16 Quite High
Bile 8 55.36 Quite High
noradrenaline 14 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 97.20 Very High Very High Very High
Obesity 86 93.16 High High
Disorder Of Lipid Metabolism 17 55.00 Quite High
Dyslipidemia /

Combined Dyslipidemia

5 52.52 Quite High
Metabolic Disorder 4 42.32 Quite Low
Metabolic Syndrome 6 39.04 Quite Low
Stress 9 26.28 Quite Low
Overweight 1 20.48 Low Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Diabetes Mellitus 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
target gene is carnitine palmitoyl transferase 1 (Cpt1), that codes for a protein important for FA transport into mitochondria [25].Whereas CPT1 is localized to the outer membrane, CPT2, that is also regulated by PPAR?
Positive_regulation (important) of CPT1
1) Confidence 0.34 Published 2010 Journal PPAR Research Section Body Doc Link PMC2933910 Disease Relevance 0.06 Pain Relevance 0.07
The induction of apoB100-LDL of genes regulating fatty acid oxidation (CPT1, PPAR?)
Positive_regulation (induction) of CPT1
2) Confidence 0.30 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582480 Disease Relevance 0.32 Pain Relevance 0.18

General Comments

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