INT252263

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (COL10A1)
Anatomy Link Frequency
chondrocyte 2
COL10A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 41 81.20 Quite High
metalloproteinase 3 51.44 Quite High
Inflammation 15 50.00 Quite Low
Pain 15 50.00 Quite Low
cytokine 4 36.16 Quite Low
Inflammatory stimuli 2 13.28 Low Low
Arthritis 4 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 41 81.20 Quite High
Disease 8 65.36 Quite High
INFLAMMATION 19 50.00 Quite Low
Pain 16 50.00 Quite Low
Apoptosis 19 45.92 Quite Low
Death 4 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These experiments show that NO helps regulate two steps in chondrocyte development, namely expression of collagen type X as well as alkaline phosphatase activity [15], illustrating just one example of a nonpathological role for NO.


Regulation (regulate) of Gene_expression (expression) of collagen type X in chondrocyte
1) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2582805 Disease Relevance 0.41 Pain Relevance 0.20

General Comments

This test has worked.

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