INT252286

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.79
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.22
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il18) extracellular region (Il18) cytoplasm (Il18)
Il18 (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 4 94.76 High High
Inflammation 56 90.40 High High
cytokine 83 90.16 High High
Central nervous system 46 87.92 High High
Arthritis 2 81.32 Quite High
rheumatoid arthritis 52 73.84 Quite High
chemokine 25 50.00 Quite Low
Multiple sclerosis 14 26.52 Quite Low
Spinal cord 14 17.64 Low Low
Hippocampus 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 71 99.96 Very High Very High Very High
Neuroblastoma 4 98.12 Very High Very High Very High
INFLAMMATION 65 90.76 High High
Alzheimer's Dementia 6 89.44 High High
Vascular Dementia 2 89.20 High High
Cognitive Disorder 12 87.36 High High
Systemic Lupus Erythematosus 2 82.20 Quite High
Arthritis 2 81.32 Quite High
Rheumatoid Arthritis 52 73.84 Quite High
Amyloid Plaque 2 50.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, a truncated form of IL-18R?
Phosphorylation (form) of IL-18R
1) Confidence 0.79 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2830964 Disease Relevance 0 Pain Relevance 0.11
Thus, on a pathway leading to AD, IL-18 may have an impact on the hyperphosphorylation of tau but also on cell cycle related mechanisms.
Phosphorylation (hyperphosphorylation) of IL-18 associated with disease
2) Confidence 0.78 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2830964 Disease Relevance 1.63 Pain Relevance 0.26
This allows an increased response to the combination of IL-12 and IL-18, leading to massive IFN-?
Phosphorylation (combination) of IL-18
3) Confidence 0.20 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2582809 Disease Relevance 0.58 Pain Relevance 0.49

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox