INT252357

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.40
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (THBS1, Cd36) transport (Cd36) mitochondrion (Cd36)
Golgi apparatus (Cd36) intracellular (Cd36) lipid binding (Cd36)
Anatomy Link Frequency
fibroblasts 1
THBS1 (Homo sapiens)
Cd36 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 89.92 High High
Kinase C 6 84.40 Quite High
rheumatoid arthritis 14 62.96 Quite High
Inflammation 49 62.72 Quite High
agonist 86 62.24 Quite High
psoriasis 1 42.32 Quite Low
chemokine 3 27.76 Quite Low
metalloproteinase 6 20.24 Low Low
ischemia 8 5.00 Very Low Very Low Very Low
dexamethasone 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Synovitis 1 98.24 Very High Very High Very High
Cancer 297 97.40 Very High Very High Very High
Immunotherapy Of Cancer 8 87.92 High High
Malignant Neoplastic Disease 22 83.84 Quite High
Pathologic Neovascularization 20 82.44 Quite High
Hematologic Neoplasms 78 77.28 Quite High
Solid Tumor 16 73.96 Quite High
Stress 3 72.96 Quite High
Metastasis 28 69.92 Quite High
Apoptosis 55 67.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A small peptide (ABT510) derived from TSP-1 type 1 repeats binds to CD36 and blocks tumorigenesis by reversing the “angiogenic switch” [229].
TSP-1 Binding (binds) of CD36
1) Confidence 0.01 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 0.82 Pain Relevance 0.06
TSP-1 is a large molecular weight glycoprotein that inhibits the proliferation and migration of ECs by interacting with CD36 expressed on the cell surface; CD36 is a PPAR?
TSP-1 Binding (interacting) of CD36
2) Confidence 0.01 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 1.35 Pain Relevance 0.03
CD47 and thrombospondin can form a trimolecular complex with CD36 expressed on synovial fibroblasts.
thrombospondin Binding (complex) of CD36 in fibroblasts
3) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2582810 Disease Relevance 0.23 Pain Relevance 0.12

General Comments

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