INT252383

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Context Info
Confidence 0.57
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.18
Pain Relevance 2.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NCF4) cytoplasm (NCF4)
Anatomy Link Frequency
face 4
NCF4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Migraine 150 100.00 Very High Very High Very High
central sensitization 10 97.32 Very High Very High Very High
allodynia 8 90.08 High High
Spinal cord 6 88.84 High High
Thalamus 2 88.20 High High
hyperexcitability 12 85.04 High High
Pain 40 65.36 Quite High
medulla 48 50.00 Quite Low
Hyperalgesia 2 40.16 Quite Low
imagery 22 32.00 Quite Low
Disease Link Frequency Relevance Heat
Headache 156 100.00 Very High Very High Very High
Congenital Anomalies 10 96.56 Very High Very High Very High
Neuropathic Pain 8 90.08 High High
Nociception 18 79.04 Quite High
Pain 46 65.36 Quite High
Urological Neuroanatomy 14 62.40 Quite High
Hyperalgesia 2 40.16 Quite Low
Disease 2 36.40 Quite Low
Migraine Disorders 4 29.44 Quite Low
Cognitive Disorder 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our migraine patients, we found that NCF activation was disrupted not only for stimuli applied to the face, but also the hand.
Negative_regulation (disrupted) of Positive_regulation (activation) of NCF in face associated with migraine
1) Confidence 0.57 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582961 Disease Relevance 1.26 Pain Relevance 1.17
The absence of a difference between migraine and control subject NCF activation for noxious stimuli to the face in migraine patients (Fig. 1) is unexpected, in light of the impaired descending modulation model.
Negative_regulation (absence) of Positive_regulation (activation) of NCF in face associated with migraine
2) Confidence 0.37 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2582961 Disease Relevance 0.92 Pain Relevance 0.91

General Comments

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