INT252419

Context Info Confidence 0.08 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.21 Pain Relevance 0.16

generation of precursor metabolites and energy (Enpp1) extracellular space (Enpp1) plasma membrane (Enpp1)

Enpp1 (Mus musculus)

Pain Link Frequency Relevance Heat adenocard 22 99.32 Glutamate 20 92.64 long-term potentiation 2 47.36 depression 7 41.76 antiepileptic Drug 8 5.00 Central nervous system 5 5.00 Glutamate receptor 4 5.00 Action potential 4 5.00 nMDA receptor 3 5.00 Neurotransmitter 3 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 1 90.80 Epilepsy 29 64.60 Convulsion 11 51.16 Depression 7 41.76 Brain Injury 1 9.08 Disease 4 5.00 Injury 3 5.00 Pain 2 5.00 Thrombosis 1 5.00 Poisoning 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The mechanism for this is that ATP is rapidly broken down into adenosine by ectonucleotidases (E-NTPDase, E-NPP, alkaline phosphatises, and ecto-5?

Phosphorylation (phosphatises) of E-NPP associated with adenocard

1) Confidence 0.08 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2583203 Disease Relevance 0.21 Pain Relevance 0.16

General Comments

This test has worked.