INT252433

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adora2b) plasma membrane (Adora2b) signal transducer activity (Adora2b)
Anatomy Link Frequency
nucleus 2
Adora2b (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 60 81.08 Quite High
Potency 26 51.48 Quite High
adenocard 71 50.00 Quite Low
antagonist 14 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Cystic Fibrosis 3 5.00 Very Low Very Low Very Low
Myocardial Infarction 3 5.00 Very Low Very Low Very Low
Infarction 3 5.00 Very Low Very Low Very Low
Cardiovascular Disease 3 5.00 Very Low Very Low Very Low
Coronary Artery Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presence of the chlorine atom at the 2-position of the purine nucleus did not seem to affect the ability of the tested compounds to activate hA2B AR, as is clear from the comparison of chlorinated derivatives 23 (hA2B EC50?
Spec (seem) Regulation (affect) of Positive_regulation (activate) of A2B in nucleus
1) Confidence 0.44 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2583210 Disease Relevance 0 Pain Relevance 0.09

General Comments

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