INT252443

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RFC1) nucleus (RFC1) intracellular (RFC1)
RFC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 60 98.58 Very High Very High Very High
adenocard 71 83.52 Quite High
Inflammation 9 64.64 Quite High
cytokine 3 55.36 Quite High
Potency 26 5.00 Very Low Very Low Very Low
antagonist 14 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 10 64.64 Quite High
Sepsis 1 61.04 Quite High
Necrosis 1 55.96 Quite High
Cancer 2 55.60 Quite High
Vasculogenic Impotence 1 50.08 Quite High
Erectile Dysfunction 2 40.08 Quite Low
Alopecia 1 29.16 Quite Low
Diabetes Mellitus 4 24.56 Low Low
Hypertension 2 24.04 Low Low
Renal Disease 1 21.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, for the time being, the selectivity profile of new potential A2B AR agonists can only be speculated in view of the ratio of binding parameters (Ki values for A1, A2A, A3 ARs) to functional parameters (EC50 for A2B, Tables 1, 2, 3, 4, 5, and 6).


Regulation (values) of A1 associated with agonist
1) Confidence 0.03 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2583210 Disease Relevance 0.35 Pain Relevance 0.59

General Comments

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