INT252453

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (AR, Adora2b) nucleoplasm (AR) transport (AR)
enzyme binding (AR) DNA binding (AR) signal transducer activity (Adora2b)
AR (Homo sapiens)
Adora2b (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 71 98.88 Very High Very High Very High
antagonist 14 92.08 High High
agonist 60 56.80 Quite High
Potency 26 41.52 Quite Low
Inflammation 9 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low
Diabetes Mellitus 4 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Cystic Fibrosis 3 5.00 Very Low Very Low Very Low
Myocardial Infarction 3 5.00 Very Low Very Low Very Low
Infarction 3 5.00 Very Low Very Low Very Low
Cardiovascular Disease 3 5.00 Very Low Very Low Very Low
Coronary Artery Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Considering the previous structure activity relationship (SAR) studies, regarding NECA and adenosine derivatives indicating the N6 as a useful position for A2B AR binding-site recognition, a new series of N6-[(substituted)phenyl/cycloalkyl/benzyl/heteroaryl-carbamoyl-methoxy-phenyl]-5?
AR Binding (recognition) of A2B associated with adenocard
1) Confidence 0.05 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2583210 Disease Relevance 0 Pain Relevance 0.35

General Comments

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