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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SLURP1) signal transduction (Adora2b) extracellular region (SLURP1)
cell adhesion (SLURP1) plasma membrane (Adora2b) signal transducer activity (Adora2b)
Adora2b (Mus musculus)
SLURP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 26 79.72 Quite High
antagonist 14 70.88 Quite High
agonist 60 62.00 Quite High
adenocard 71 50.00 Quite Low
Inflammation 9 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 4 58.24 Quite High
Dyslipidemia /

Combined Dyslipidemia

1 56.88 Quite High
Metabolic Syndrome 2 55.76 Quite High
Diabetes Mellitus 4 53.92 Quite High
Muscle Hypertonia 1 49.04 Quite Low
Hypertension 2 25.28 Quite Low
Cardiovascular Disease 3 23.20 Low Low
Thrombosis 1 22.00 Low Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 3-methoxyphenyl derivative 51 and the 4-methoxyphenyl derivative 52 also showed appreciable selectivity for A2B versus A2A ARs (3- and 24-fold, respectively) but reduced selectivity for A2B versus A3 ARs (2.1- and 2.6-fold, respectively) in comparison with the corresponding 3/4-hydroxyphenyl analogues 50 (Ki A2A/EC50 A2B?
Negative_regulation (reduced) of A2B Binding (selectivity) of ARs
1) Confidence 0.02 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2583210 Disease Relevance 0.27 Pain Relevance 0.16

General Comments

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