INT252596

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cxcr3) plasma membrane (Cxcr3) signal transducer activity (Cxcr3)
Anatomy Link Frequency
lymph node 2
Cxcr3 (Mus musculus)
Pain Link Frequency Relevance Heat
interstitial cystitis 41 96.64 Very High Very High Very High
chemokine 12 77.52 Quite High
Inflammation 24 67.12 Quite High
Lasting pain 1 51.40 Quite High
cytokine 14 20.00 Low Low
Inflammatory response 1 15.84 Low Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cystitis 70 99.80 Very High Very High Very High
Interstitial Cystitis 41 96.64 Very High Very High Very High
Disease 16 72.44 Quite High
INFLAMMATION 24 67.12 Quite High
Infection 2 56.44 Quite High
Fever 1 55.72 Quite High
Cancer 2 54.92 Quite High
Pain 1 51.40 Quite High
Urinary Tract Disease 1 37.84 Quite Low
Diabetes Mellitus 2 25.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These clinical trends were consistent with CYP-induced cystitis in mice; CXCR3 ligands were elevated in mouse serum as well as urinary bladder and iliac lymph node lymphocytes.
Positive_regulation (elevated) of CXCR3 Binding (ligands) of in lymph node associated with cystitis
1) Confidence 0.49 Published 2008 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC2583981 Disease Relevance 1.19 Pain Relevance 0.41

General Comments

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