INT252631

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Casp3, Tnfrsf1a) mitochondrion (Casp3) intracellular (Casp3)
protein complex (Tnfrsf1a) cytoplasm (Casp3) cytosol (Casp3)
Casp3 (Rattus norvegicus)
Tnfrsf1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 9 87.12 High High
ischemia 28 84.76 Quite High
cerebral cortex 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Intracerebroventricular 3 5.00 Very Low Very Low Very Low
medulla 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 98.16 Very High Very High Very High
Targeted Disruption 43 91.92 High High
Infarction 4 87.92 High High
Brain Hemorrhage 17 84.76 Quite High
Brain Injury 1 79.88 Quite High
Stroke 6 70.64 Quite High
Stress 3 51.56 Quite High
Middle Cerebral Artery Infarction 31 5.28 Low Low
Apoptosis 19 5.00 Very Low Very Low Very Low
Death 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
to p55/TNFR1 will recruit TRADD, activate effector caspase-8, and cleave the executioner caspase-3 for activation [43].
caspase-3 Binding (recruit) of TNFR1
1) Confidence 0.10 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2583993 Disease Relevance 0.69 Pain Relevance 0.13

General Comments

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