INT252700

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (FBN1) extracellular region (FBN1) proteinaceous extracellular matrix (FBN1)
FBN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 21 92.56 High High
COX2 1 28.04 Quite Low
Inflammation 48 5.00 Very Low Very Low Very Low
fibrosis 19 5.00 Very Low Very Low Very Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 45 95.28 Very High Very High Very High
Apoptosis 55 60.96 Quite High
Wound Healing 12 50.00 Quite Low
Stress 107 5.00 Very Low Very Low Very Low
INFLAMMATION 57 5.00 Very Low Very Low Very Low
Death 55 5.00 Very Low Very Low Very Low
Injury 46 5.00 Very Low Very Low Very Low
Liver Disease 43 5.00 Very Low Very Low Very Low
Fibrosis 37 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 27 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In 2003, Bataller and coworkers [318] were the first to identify the presence of components of NOX in HSC/MFs, suggesting that the pro-fibrogenic action of Ang II, as already delineated in in vivo and in vitro studies [319,320], is dependent on the associated activation of NOX and the related ROS-dependent activation of MAPKs, phosphorylation of c-Akt and increased AP-1 DNA binding activity [318], events blocked by the specific NOX inhibitor DPI (diphenyl-phenyleneiodonium) or the inhibitor of Ang II type 1 receptor (AT1), losartan.
Phosphorylation (phosphorylation) of MFs
1) Confidence 0.00 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 0.27 Pain Relevance 0.09

General Comments

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