INT252728

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Context Info
Confidence 0.33
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.39
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 1
FBRS (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 23 99.96 Very High Very High Very High
addiction 45 98.44 Very High Very High Very High
Inflammation 69 96.36 Very High Very High Very High
Morphine 36 73.48 Quite High
Kinase C inhibitor 1 70.24 Quite High
Inflammatory response 11 69.88 Quite High
fibrosis 19 46.48 Quite Low
opiate 2 23.92 Low Low
tolerance 2 19.12 Low Low
chemokine 6 12.88 Low Low
Disease Link Frequency Relevance Heat
Liver Disease 43 99.62 Very High Very High Very High
INFLAMMATION 78 96.36 Very High Very High Very High
Cardiovascular Disease 13 93.24 High High
Disorder Of Lipid Metabolism 20 91.56 High High
Obesity 72 86.92 High High
Myocardial Infarction 6 83.60 Quite High
Apoptosis 55 81.40 Quite High
Stress 107 74.88 Quite High
Nicotine Addiction 20 74.84 Quite High
Metabolic Syndrome 4 67.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nevertheless, LPS requires one or several partner components to be present in the FBS in order to activate TLR4.
Gene_expression (present) of FBS
1) Confidence 0.33 Published 2010 Journal J Inflamm (Lond) Section Body Doc Link PMC2819999 Disease Relevance 0.16 Pain Relevance 0.04
ms after the offset of the center object send precise timed FBs to excite and fire neurons in between the center of field of view representation in area 17 and the retinotopic flanking positions (Ahmed et al., 2008).
Gene_expression (excite) of FBs in neurons
2) Confidence 0.10 Published 2010 Journal Frontiers in Systems Neuroscience Section Body Doc Link PMC2906257 Disease Relevance 0 Pain Relevance 0
Even though, FBS reduced in the opium addicted subjects but it was not significant.
Gene_expression (reduced) of FBS
3) Confidence 0.08 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2588593 Disease Relevance 1.25 Pain Relevance 0.11
Regardless to the route of administration as shown in table 3, i) FBS reduced nonsignificantly when the duration of addiction increased. ii).
Gene_expression (reduced) of FBS associated with addiction
4) Confidence 0.08 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2588593 Disease Relevance 0.49 Pain Relevance 0.42
Accordingly, the lipid soluble aldehyde HNE, at levels compatible with those described in CLDs, up-regulates the expression of the pro-fibrogenic cytokine TGF?
Gene_expression (expression) of pro-fibrogenic associated with liver disease and cytokine
5) Confidence 0.01 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 0.49 Pain Relevance 0.13

General Comments

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