INT252746

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.41
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTPRC)
Anatomy Link Frequency
neutrophils 1
PTPRC (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 11 98.40 Very High Very High Very High
Inflammation 48 61.20 Quite High
cytokine 21 45.20 Quite Low
chemokine 6 39.80 Quite Low
fibrosis 19 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Nerve growth factor 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 57 98.20 Very High Very High Very High
Apoptosis 55 97.20 Very High Very High Very High
Calcification 2 63.68 Quite High
Wound Healing 12 50.00 Quite Low
Liver Disease 43 49.68 Quite Low
Stress 107 35.28 Quite Low
Death 55 32.72 Quite Low
Hepatotoxicity 2 19.40 Low Low
Gallstones 3 5.56 Low Low
Injury 47 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Over 90% MSC expressed the phenotype of CD45 ?
Phosphorylation (phenotype) of CD45
1) Confidence 0.24 Published 2010 Journal Asian Journal of Transfusion Science Section Body Doc Link PMC2847339 Disease Relevance 0.06 Pain Relevance 0
Third, ROS may have a role in the apoptosis-related removal of leukocytes during inflammatory responses, as clearly shown for neutrophils and other cells, again by involving tyrosine phosphorylation, CD45 and SHP-1 [261-264], but also through the NOX-dependent, Lyn-mediated activation of the inositol phosphatase SHIP [265].
Phosphorylation (phosphorylation) of CD45 in neutrophils associated with inflammatory response and apoptosis
2) Confidence 0.15 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 0.34 Pain Relevance 0.08

General Comments

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