INT252753

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.35
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (RAF1) cytoplasm (RAF1) cytosol (RAF1)
cell proliferation (RAF1) signal transduction (RAF1) nucleus (RAF1)
RAF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 5 91.44 High High
Inflammation 48 57.80 Quite High
fibrosis 19 40.48 Quite Low
ischemia 1 11.04 Low Low
cytokine 21 5.00 Very Low Very Low Very Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatitis C Virus Infection 27 98.16 Very High Very High Very High
Stress 107 89.60 High High
Disease 18 89.04 High High
Targeted Disruption 3 73.76 Quite High
Infection 5 68.24 Quite High
Hepatocellular Cancer 1 66.40 Quite High
INFLAMMATION 57 57.80 Quite High
Injury 46 50.36 Quite High
Wound Healing 12 50.00 Quite Low
Iron Overload 5 48.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
First, only some HCV-related proteins, such as NS5A, NS3 and HCV core protein, are likely to play roles in mediating redox perturbations, which can include increased generation of both ROS and RNS, iNOS and COX-2 (NS5A and C).
Positive_regulation (increased) of Localization (generation) of NS5A associated with hepatitis c virus infection
1) Confidence 0.06 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 1.35 Pain Relevance 0.07

General Comments

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