INT252787

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (FCGR3B, ROS1) cell differentiation (ROS1) cell proliferation (ROS1)
extracellular region (FCGR3B)
Anatomy Link Frequency
neutrophils 1
FCGR3B (Homo sapiens)
ROS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 6 77.28 Quite High
cytokine 21 76.68 Quite High
Inflammation 48 76.28 Quite High
Inflammatory response 11 38.48 Quite Low
fibrosis 19 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 57 76.28 Quite High
Stress 107 72.76 Quite High
Death 55 70.20 Quite High
Apoptosis 55 60.04 Quite High
Liver Disease 43 57.20 Quite High
Hepatotoxicity 2 56.88 Quite High
Wound Healing 12 50.00 Quite Low
Gallstones 3 43.04 Quite Low
Alcoholic Liver Diseases 19 39.76 Quite Low
Injury 46 12.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
First, ROS are likely to be involved in the process of phagocytosis, possibly by leading to amplification of the stimulating signal that follows engagement of Fc receptors on the surface of phagocytic cells, as reported for neutrophils, where ROS seem able to increase either the cross-linking of the FcãRIIIb [254], as well as by contributing, in neutrophils and macrophages, to amplification of the signal by modulating the activity of the tyrosine kinase Syk, a FcãR downstream signalling element [255].
Fc RIIIb Binding (linking) of ROS in neutrophils
1) Confidence 0.06 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 0.58 Pain Relevance 0.20

General Comments

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