INT252823

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TNF, SIGMAR1) transport (SIGMAR1) nuclear envelope (SIGMAR1)
endoplasmic reticulum (SIGMAR1) intracellular (TNF) extracellular matrix organization (TNF)
TNF (Homo sapiens)
SIGMAR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 48 96.20 Very High Very High Very High
cytokine 21 5.00 Very Low Very Low Very Low
fibrosis 19 5.00 Very Low Very Low Very Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 55 97.80 Very High Very High Very High
INFLAMMATION 57 96.20 Very High Very High Very High
Liver Disease 43 94.16 High High
Apoptosis 55 79.72 Quite High
Wound Healing 12 50.00 Quite Low
Stress 107 34.24 Quite Low
Injury 46 5.00 Very Low Very Low Very Low
Cirrhosis 45 5.00 Very Low Very Low Very Low
Fibrosis 37 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 27 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TNF interaction with its type I receptor will generate a complex sequence of events (more detail is given in Figure 23) that are designed to lead either to survival or cell death, with ROS forcing them towards the latter [197-202].
TNF Binding (interaction) of type I receptor associated with death
1) Confidence 0.01 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 0.95 Pain Relevance 0.05

General Comments

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