INT252846

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Context Info
Confidence 0.73
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC4A1) transmembrane transport (SLC4A1)
SLC4A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 1 58.64 Quite High
backache 2 57.52 Quite High
Spinal cord 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 107 99.30 Very High Very High Very High
Chordoma 9 89.52 High High
Carcinoma 17 89.00 High High
Ependymoma 37 88.12 High High
Glioma 4 63.52 Quite High
Low Back Pain 2 57.52 Quite High
Severe Combined Immunodeficiency 2 44.40 Quite Low
Osteogenic Sarcomas 1 43.84 Quite Low
Nerve Root Compression 1 25.20 Quite Low
Metastasis 31 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The tumour cells in both cases showed strong positivity for cytokeratin markers, AE1AE3 (figure 5a), CAM 5.2 (figure 5b) and focally for cytokeratin 7.
Localization (positivity) of AE1 associated with cancer
1) Confidence 0.73 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2584038 Disease Relevance 1.08 Pain Relevance 0.09
E12 (M0630, 1:100, 1 hr; Dako, Mississauga, ON), mouse monoclonal Vimentin (Vim3B4, 1:200, 1 hr; American Research Products, Belmont, MA), mouse monoclonal E-cadherin (36B5, 1:100, overnight; Vector Labs, Burlington, ON), mouse monoclonal p63(7JUL, 1:50, 2 hrs; Vector Labs) and human cytokeratin cocktail (AE1/AE3, 1:200, 1 hr; Dako).
Localization (1:200) of AE1
2) Confidence 0.73 Published 2010 Journal BMC Clin Pathol Section Body Doc Link PMC2829523 Disease Relevance 0 Pain Relevance 0

General Comments

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