INT252897

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PTTG1IP, PTTG1) cytoplasm (PTTG1IP, PTTG1) cytosol (PTTG1)
mitosis (PTTG1) chromosome organization (PTTG1) chromosome segregation (PTTG1)
PTTG1IP (Homo sapiens)
PTTG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 2 81.64 Quite High
metalloproteinase 18 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ovarian Cancer 32 75.16 Quite High
Pituitary Cancer 26 74.44 Quite High
Cancer 174 5.00 Very Low Very Low Very Low
Targeted Disruption 54 5.00 Very Low Very Low Very Low
Apoptosis 36 5.00 Very Low Very Low Very Low
Metastasis 24 5.00 Very Low Very Low Very Low
Aneuploidy 16 5.00 Very Low Very Low Very Low
Thyroid Neoplasm 12 5.00 Very Low Very Low Very Low
Hyperplasia 10 5.00 Very Low Very Low Very Low
Breast Cancer 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chien and Pei [23] showed that PTTG1 was associated with PTTG1-binding factor (PBF).
PBF Binding (associated) of PTTG1
1) Confidence 0.04 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 0.15 Pain Relevance 0.04
In the same study, the co-expression of a PBF mutant that lacks its NLS was unable to bind to PTTG1 and failed to promote PTTG nuclear accumulation.


PBF Neg (unable) Binding (bind) of PTTG1
2) Confidence 0.04 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 0 Pain Relevance 0

General Comments

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