INT252902

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.50
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PTTG1, MMP2) chromosome segregation (PTTG1) cytoplasm (PTTG1)
cytosol (PTTG1) peptidase activity (MMP2) extracellular space (MMP2)
PTTG1 (Homo sapiens)
MMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 9 100.00 Very High Very High Very High
Pain 1 31.92 Quite Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 12 99.26 Very High Very High Very High
Apoptosis 18 92.88 High High
Cancer 87 87.44 High High
Adenocarcinoma 2 75.88 Quite High
Death 2 70.08 Quite High
Skin Cancer 2 69.72 Quite High
Aggression 1 65.32 Quite High
Recurrence 1 64.48 Quite High
Breast Cancer 5 60.88 Quite High
Ovarian Cancer 16 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since PTTG1 has been reported to have a role in angiogenesis and metastasis [19,55,79], we hypothesize that the regulation of MMP-2 by PTTG1 is one of the mechanisms by which PTTG1 contributes to angiogenesis and metastasis.


PTTG1 Regulation (regulation) of MMP-2 associated with metalloproteinase and metastasis
1) Confidence 0.01 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 1.50 Pain Relevance 0.14

General Comments

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